2008-01-17T14:30:00.000-08:00

Azerbaijani Blog

The cancer stem cells share many characteristics with normal stem cells, including self-renewal and differentiation.
With the growing evidence that cancer stem cells exist in a wide arrayof tumors, it is becoming increasingly important to understandthe molecular mechanisms that regulate self-renewal and differentiationbecause corruption of genes involved in these pathways likely participates in tumor growth.

This new paradigm of oncogenesis has been validated in a growing list of tumors. Studies of normaland cancer stem cells from the same tissue have shed light on theontogeny of tumors. That signaling pathways such as Bmi1 and Wnt have similar effects in normal and cancer stem cell self-renewal suggests that common molecular pathways regulate both populations.Understanding the biology of cancer stem cellswill contribute to theidentification of molecular targetsimportant for future therapies.
Source:

The Biology of Cancer Stem Cells - Annual Review of Cell and

Other Related Links:

Cancer biology: Summing up cancer stem cells

Probing the Biology of Cancer Stem Cells

Cancer Stem Cell Research Program Launched By Rochester

Defining the Molecular Determinants of Myogenic Commitment

Michael Rudnicki's laboratory uses molecular genetic approaches to determine the function and roles of genes that regulate cellular proliferation and differentiation of stem cells. They identified Pax7 as a transcription factor required for the specification of satellite cells and identified Wnt signaling as playing an important role in the myogenic specification of adult stem cells.

In adult skeletal muscle, satellite cells reside beneath the basal lamina of muscle, closely juxtaposed to muscle fibers, and make up 2-7 percent of the nuclei associated with a particular fiber. Satellite cells are normally mitotically quiescent but are activated (they enter the cell cycle) in response to stress induced by weight bearing or by trauma. The descendants of activated satellite cells, called myogenic precursor cells, undergo multiple rounds of division before fusion and terminal differentiation.

Source:

Pax7 as a transcription factor required for the specification of satellite cells and identified Wnt signaling

Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex

Links:

Pax-7 up-regulation inhibits myogenesis ... tial mechanism for self-renewal

Pax7 Reveals a Greater Frequency and Concentration of Satellite Cells at the Ends of Growing Skeletal Muscle Fibers

Regeneration of injured muscle from adult stem cells

Muscle satellite cells adopt divergent fates : a mechanism for self-renewal?

Pax7 Reveals a Greater Frequency and Concentration of Satellite Cells at the Ends of Growing Skeletal Muscle Fibers

Megf10 regulates the progression of the satellite cell myogenic program

Pax7 directs postnatal renewal and propagation of myogenic

Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells

Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification

The biology of cancer stem cells

Increased survival of
muscle stem cells lacking the MyoD
gene after transplantationinto
regenerating skeletal muscle

MyoD is a myogenic master transcription factor that plays an essential role in muscle satellite cell (muscle stem cell) differentiation. To further investigate the function of MyoD in satellite cells, we examined the transplantation of satellite cell-derived myoblasts lacking the MyoD gene into regenerating skeletal muscle.

Source:

Increased survival of muscle stem cells

Drugs for Your Genes:
ScienCentral News Video

Hydrogen Fuel Advance

New preventive biomedicine
with fast genetic diagnostics

Names of vodeos (left to right):
1)Gliadel Wafer Mechanism
2)Brain Tumor (Glioblastoma)
Treatment with GEMM
3)The Estrogen Receptor (I):
Hormonal Mechanisms in the Body
4)Organic Chemistry Lab Demo:
Extractions (short version)
5)Sirtris and Harvard
Discover New Mechanism to Slow Aging
6)Micro and nanotechnologies
are revolutionising medicine

Stem Cell Research: Where
Science Meets Politics and Ethics

George Daley on Korean stem
cells' true source

Gold Nanoparticles and Cancer Cell Detection

The Genome: A One-Minute
Explanation

Interview with Sydney Brenner
- August 2007 - part 1

Names of vodeos (left to right):
1)Health Matters: Fertility
and In Vitro Fertilization (IVF)
2)Proteins: Assemblies in Action
3)Profiles in Discovery:
Russell Doolittle
4)Cardiovascular Update:
Coronary Artery Plaques
5)Stem Cells: The Brain's
Beginnings
6)Health Matters:
Stem Cell Research

Charlie Rose - ERIC KANDEL
(FROM 8/7/01)

Dr Francis Collins interview on CNN

Breakthroughs
in Cancer Treatment II

Microarray Method
for Genetic Testing

What is a Chalazion?
A chalazion is a tiny lump of the upper or lower eyelid caused by inflammation of a gland of the lid. It may be soft and fluid-filled or firmer. A chalazion is also referred to as a meibomian cyst, tarsal cyst, or conjunctival granuloma.

What are these eyelid glands?
Eyelid glands are called the meibomian glands. They are also known as the palpebral glands, tarsal glands, or tarsoconjunctival glands. There are 30 to 40 of these glands in each of the upper and lower lids. The tiny openings of each of these oil or sebaceous glands are just behind the lid lashes at the lid margins. These glands produce a thick liquid secretion that is discharged into the tear film of the eye. This liquid is a mixture of oil and mucus and is called sebum. The liquid acts to lubricate the surface of the eye.

Source:

What is a chalazion?

Links:

شالازیون (Chalazion)

Chalazion
From Wikipedia, the free encyclopedia

A chalazion is a lump in the eyelid

جراحی شالازیون

şalazyon:gözümün üst kapağında şalazyon çıktı

sol göz kapağının iç yüzünde saptanan şalazyon benzeri lipogranülomatöz

GÖZ KAPAK HASTALIKLARI

Hagelkorn (Chalazion

Unter einem Hagelkorn (Chalazion) versteht man eine nicht-infektiöse, lokalisierte Entzündung einer Meibom-Drüse am Auge

Als Chalazion, Hagelkorn, wird eine von einer Meibom-Drüse ausgehende granulomatöse Entzündung bezeichnet

Orgelet et chalazion

Le chalazion se définit par l'inflammation et l'enkystement d'une ou plusieurs glandes de Meibomius au niveau de la paupière

This is a focal inflammation of the eyelid caused by obstruction of a meibomian gland

Халазион (градина)- хроническое воспалительное заболевание хрящевой ткани около одной или нескольких мейбиевых желез

Халазион

شالازیون یکی دیگر از توده‌های لبه پلک است که در ابتدا تظاهری شبیه گل مژه دارد

شالازیون از ریشه یونانی و به معنای "توده کوچک "است و اندازه آن می تواند از ته سنجاق تا یک نخود درشت متفاوت باشد

Göz kapaklarında pek çok yağ bezi vardır

شالازیون عبارتست از یک کیست که در پلک ایجاد شده و علت آن انسداد مجرای یکی از غدد موجود در پلک میباشد

شالازیون های بزرگ بزرگ به خصوص در پلك بالایی روی قرنیه فشار می آورند و با تغییر شكل قرنیه باعث ایجاد آستیگماتیسم و تاری دید می شوند

Un chalazion es una ampliación de una glándula productora de aceite en el párpado llamado la glándula meibomian

Homeopatia y Oftalmologia:Chalazion

El término chalazión o quiste de Meibomio

Lipogranuloma de glándula de Meibomio

Chalazion eye surgery

If your eyelid has a small lump in, and is red, painful, and swollen, treat like a stye as above

Eyelid Cyst Removal (Chalazion Excision)

A stye is an infected sebaceous gland, usually at the edge of the eyelid

To determine if bacteria are present or if the lump

The ABCs of Malignancies: Diagnosing Lumps on the Lids and Conjunctiva

I've had a stye on my upper lid for a few months

What are styes and chalazia?

Eyelid and Tear Gland Disorders

Blepharitis

Células madre: las neuronas
se recuperan

The Life of Cellular Slime moid

Dr. Lipton began his scientific career as a cell biologist. He received his Ph.D. Degree from the University of Virginia at Charlottesville before joining the Department of Anatomy at the University of Wisconsin’s School of Medicine in 1973. Dr. Lipton’s research on muscular dystrophy, studies employing cloned human stem cells, focused upon the molecular mechanisms controlling cell behavior. An experimental tissue transplantation technique developed by Dr. Lipton and colleague Dr. Ed Schultz and published in the journal Science was subsequently employed as a novel form of human genetic engineering.

Source:

Dr. Lipton began his scientific career as a cell biologist

Dr. Bruce Lipton author of BIOLOGY OF BELIEF: Unleashing the Power of Consciousness

Bruce Lipton - Death as
a Form of Creation

Epigenetics: Your Unlimited
Potential for Health
Dr. Bruce Lipton explains
how we are not limite

Dr. Bruce Lipton

Why Egypt?, A conversation with Bruce Lipton and Nicki

Plastic Bottle Chemical

Drugs for Brain Tumors

New Innovations in Heart
and Lung Transplantation

Beating Brain Cancer

Brain Tumor

Epigenetica: Una nueva
rama de la Genética

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